Purified NA/LE Rat Anti-Mouse CD4

產品名稱:Purified NA/LE 大鼠抗小鼠 CD4 抗體；Purified NA/LE Rat Anti-Mouse CD4

中文名稱:Purified NA/LE 大鼠抗小鼠 CD4 抗體

英文名稱:Purified NA/LE Rat Anti-Mouse CD4

Purified NA/LE Rat Anti-Mouse CD4 產品介紹：

Material Number: 553726
Alternate Name: L3T4
Size: 0.5 mg
Concentration: 1.0 mg/ml
Clone: GK1.5
Immunogen: Mouse CTL clone V4
Isotype: Rat (LEW) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative,
0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of
protein as determined by the LAL assay.

Purified NA/LE Rat Anti-Mouse CD4 Description：

The GK1.5 clone has been reported to react with the CD4 (L3T4) differentiation antigen expressed on most thymocytes, a subpopulation of
mature T lymphocytes (i.e., MHC class II-restricted T cells, including most T helper cells), and a subset of NK-T cells. In addition, CD4 has
also been reported to be detectable on pluripotent hematopoietic stem cells, bone marrow myeliod and B-lymphocyte precursors, intrathymic
lymphoid precursors, and a subset of splenic dendritic cells. CD4 has also been reported to be expressed on the plasma membrane of mouse
egg cells and is involved in adhesion of the egg to MHC class II-bearing sperm. CD4 is an antigen coreceptor on the T-cell surface which
interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell
receptor complex and protein tyrosine kinase lck. GK1.5 mAb reportedly blocks binding of the RM4-5 (Cat. No. 553046/553047) and
H129.19 (Cat. No. 553650/553651), but not RM4-4 (Cat. No. 553055) antibodies.

Purified NA/LE Rat Anti-Mouse CD4 Preparation and Storage：

Store undiluted at 4°C.
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
This preparation contains no preservatives, thus it should be handled under aseptic conditions