產品名稱:Biotin Mouse Anti-CD138
Biotin Mouse Anti-CD138 產品介紹:
Material Number: 553713 Alternate Name: Syndecan-1 Size: 0.5 mg Concentration: 0.5 mg/ml Clone: 281-2 Immunogen: NAMRU mouse mammary gland epithelial cell line NMuMG Isotype: Rat (F344) IgG2a, κ Reactivity: QC Testing: Mouse Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
Biotin Mouse Anti-CD138 Description:
The 281-2 antibody reacts with the core protein of CD138 (Syndecan-1), a cell-surface, integral membrane heparan sulfate- and chondroitin sulfate-containing proteoglycan that binds to interstitial extracellular matrix molecules. Syndecan-1 is predominantly expressed on epithelial cells, where its expression correlates with normal epithelial organization. It is also expressed on B lymphocytes at specific stages during their differentiation: precursor B cells in the bone marrow and antibody-secreting cells, including plasma cells, but not mature peripheral B cells. It is thus implicated in mediating B cell-matrix interactions. CD138 expression is also regulated during embryonic development, and the molecule shows a tissue- specific structural polymorphism resulting from different post-translational modifications. The 281-2 antibody may be used to detect the differently glycosylated forms, because it reacts with the core protein. Furthermore, the mAb detects the Syndecan-1 ectodomain which is cleaved from cell surfaces by a metalloproteinase
Biotin Mouse Anti-CD138 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
Biotin Mouse Anti-CD138 Suggested Companion Products:
Catalog Number Name Size Clone 554061 PE Streptavidin 0.5 mg (none) 553087 FITC Rat Anti-Mouse CD45R/B220 0.1 mg RA3-6B2 553928 Biotin Rat IgG2a κ Isotype Control 0.25 mg R35-95
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