PE Mouse Anti-Rat CD4

產品名稱:PE 小鼠抗大鼠 CD4 抗體；PE Mouse Anti-Rat CD4

中文名稱:PE 小鼠抗大鼠 CD4 抗體

英文名稱:PE Mouse Anti-Rat CD4

PE Mouse Anti-Rat CD4 產品介紹：

Material Number: 551397
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: OX-38
Immunogen: Rat thymocyte glycoproteins
Isotype: Mouse (BALB/c) IgG2a, κ
Reactivity: QC Testing: Rat
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.


PE Mouse Anti-Rat CD4 Description：

The OX-38 antibody has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e., 
MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, and some dendritic cells. CD4 is an antigen 
coreceptor on the T-cell surface which interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation 
through its association with the T-cell receptor complex and protein tyrosine kinase lck. The OX-38 antibody has been reported to bind to the 
same epitope of CD4 as that recognized by W3/25 mAb, which is a different epitope than that recognized by OX-35 mAb (Cat. No. 554837). 
In vivo blocking of some cell-mediated immune responses by mAb OX-38 has been reported. Injection of OX-38 mAb induces allograft 
unresponsiveness in rats, with varying results depending on the rat strain used (high or low responder). Furthermore, in vivo depletion of 
CD4+ lymphocytes has been reported with this antibody.

PE Mouse Anti-Rat CD4 Preparation and Storage：

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.