產品名稱:PE 小鼠抗大鼠 CD86 抗體;PE Mouse Anti-Rat CD86
中文名稱:PE 小鼠抗大鼠 CD86 抗體
英文名稱:PE Mouse Anti-Rat CD86
PE Mouse Anti-Rat CD86 產品介紹:
Material Number: 551396 Alternate Name: B7-2 Size: 0.1 mg Concentration: 0.2 mg/ml Clone: 24F Immunogen: HTLV-1-transformed rat T-cell line Lewis-S1 Isotype: Mouse (BALB/c) IgG1, κ Reactivity: QC Testing: Rat Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide PE Mouse Anti-Rat CD86 Description:
The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24F mAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates.
PE Mouse Anti-Rat CD86 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed by gel filtration chromatography. Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.
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