重組食蟹猴 aFGF / FGF1 蛋白|Fibroblast growth factor 1 (acidic) Protein|廠家現貨|參數

aFGF / FGF1蛋白產品信息
產品名稱：重組食蟹猴 aFGF / FGF1 蛋白|Fibroblast growth factor 1 (acidic) Protein|廠家現貨|參數
別名: FGF1
表達方式: A DNA sequence encoding the cyno FGF1 (Phe16-Asp155) was expressed and purified  with an initial Met.
種屬: Cynomolgus
表達宿主: E.coli

aFGF / FGF1 Protein QC Testing
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: Please contact us for more information.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Met
分子量: The recombinant cyno FGF1 consists of 141 amino acids and has a calculated molecular mass of 16 kDa. It migrates as an 16 KDa band in SDS-PAGE under reducing conditions.
緩沖液: Lyophilized from sterile PBS, pH 7.4, 20% glycerol.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

aFGF / FGF1 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
aFGF / FGF1蛋白背景綜述
aFGF (Acidic fibroblast growth factor), also known as FGF1 (Fibroblast growth factor 1), FGF-acidic and HBGF-1 (Heparin-binding growth factor 1), is a member of the fibroblast growth factor (FGF) family. It is a powerful mitogen exhibiting strong action on numerous different cell types. FGF1 protein plays a role in various stages of development and morphogenesis, as well as in angiogenesis and wound healing processes. aFGF protein binds to cell surface receptors with high affinity with the prerequisite association of aFGF with heparan sulfate. The aFGF gene is a repressed target of p53. It inhibits both p53-dependent apoptosis and cell growth arrest via an intracrine pathway. Accordingly, aFGF and p53 pathways may interact in the cell to determine cell fate.
參考文獻
Rothlein, R. et al.,1986, Journal of Immunology. 137 (4): 1270-4.
Yang, L. et al., 2005, Blood. 106 (2): 584-92.
Gorczynski, R.M., 2005, Curr Opin Invest Drugs. 6: 483-7.
Frijns, C.J. et al., 2002, Stroke. 33 (8): 2115-22.
Bella, J. et al., 1998, Proc Natl Acad Sci. 95 (8): 4140-5.

包裝：50ug

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