重組人 IL-8 (aa 6-77) 蛋白|IL8(aa 6-77) Protein|產品詳情|參數

IL-8(aa 6-77) 蛋白產品信息
產品名稱：重組人 IL-8 (aa 6-77) 蛋白|IL8(aa 6-77) Protein|產品詳情|參數
IL-8 別名: CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF,
表達方式: The 72 amino acid residue form (Ser 28- Ser 99) of mature human IL8 (NP_000575.1) was expressed and purified.
種屬: Human
表達宿主: Human Cells

IL-8(aa 6-77) 蛋白質控指標
純度: > 95% as determined by SDS-PAGE. SDS-PAGE:
內**: < 1.0 EU per 1μg of the protein as determined by the LAL method.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Ser 28
分子量: The recombinant human cytokine IL8 isoform comprising 72 amino acids predicts a molecular mass of 8.5 kDa, and migrates as an approximately 12kDa protein in SDS-PAGE.due to glycosylation.
緩沖液: Lyophilized from sterile 100mM NaCl, 50mM Tris, pH7.5

IL-8(aa 6-77) 蛋白使用指南
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage and usage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

IL-8(aa 6-77) 蛋白背景綜述
Interleukin-8 (IL8), also known as CXCL8, is a member of the CXC chemokine family of small (8–10 kDa) proteins, a subfamily of chemokines within the cytokine superfamily. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli (IL-1, TNF, LPS, etc). IL8 has the N-terminal tripeptide Glu-Leu-Arg (ELR) motif, which is known to mediate IL8 receptor binding and subsequent signal transduction, such as the TRAF6- NF-κB pathway, and involved in inflammatory and allergic responses. Furthermore, it has been shown that IL8 also plays a vital role in angiogenesis which is important for tumorigenesis, progression and metastasis, and accordingly the expression levels of IL8 correlate with disease progression in several human carcinomas. Multiple N-terminal processed forms for this protein are available, and this purified IL8 (6-77 amino acids) is the most prominent one.

參考文獻
Baqqiolini, M. et al., 1992, FEBS. Lett. 307: 97-101
Koch, A.E. et al., 1992, Science. 258: 1798-1801.
Bar-Eli, M. et al., 1999, Pathobiology. 67: 12-18.
Charalambous, C. et al., 2005, Cancer. Res. 65: 10347-10354.
Manna, S.K. et al., 2005, J. Biol. Chem. 280: 7010-7021.

包裝：50ug

1、產品質量問題，在產品售出7日內提出異議并且產品未有損壞，試劑類產品，需要提供詳細的檢測數據，創賽負責免費退換貨服務；
2、本產品屬于消耗品，不提供質保服務；
3、所有產品售后問題，請直接聯系我司，我們將會盡快為您響應處理
查詢關鍵詞：重組人 IL-8 (aa 6-77) 蛋白，IL8(aa 6-77) Protein，產品詳情，參數，原料藥，大包裝定制，現貨促銷，醫藥中間體，科學儀器，實驗室耗材，生化試劑，創賽中國,細胞因子
CANSPEC品質提供的重組人 IL-8 (aa 6-77) 蛋白|IL8(aa 6-77) Protein|產品詳情|參數性能**，其優良的品質滿足您不同實驗的多種需求。
本產品由上海創賽品質提供，歡迎咨詢國內免費服務專線：400-608-7598，更多產品信息請登錄m.aysxmc.cn或www.4006087598.com