重組小鼠 CXCL16 / SRPSOX 蛋白|C-X-C motif chemokine 16 ( CXCL16 / SRPSOX ) Protein

CXCL16 / SRPSOX蛋白產品信息
產品名稱：重組小鼠 CXCL16 / SRPSOX 蛋白|C-X-C motif chemokine 16 ( CXCL16 / SRPSOX ) Protein
Synonym: DN-491F10.6  , 0910001K24Rik  , AV290116  , BB024863  ,  SR-PSOX, Zmynd15 ,   CXCL16
表達方式: A DNA sequence encoding the mouse CXCL16 (NP_075647.3) extracellular domain (Met 1-Trp 201 ) was expressed, with a C-terminal polyhistidine tag
種屬: Mouse  
表達宿主: Human Cells

CXCL16 / SRPSOX蛋白質控指標
純度: > 95 % as determined by SDS-PAGE SDS-PAGE
內**: < 1.0 EU per 1μg of the protein as determined by the LAL method.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Asn 27
分子量: The recombinant mouse CXCL16 comprises 186 amino acids with a predicted molecular mass of 20.5 kDa. As a result of glycosylation, the apparent molecular mass of rm CXCL16 is approximately 35-40 kDa in SDS-PAGE under reducing conditions
緩沖液: Lyophilized from sterile PBS ,   pH 7.4

CXCL16 / SRPSOX蛋白使用指南
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CXCL16 / SRPSOX蛋白背景綜述
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. It is expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. It is weakly expressed in heart and liver and no expression in brain and bone marrow. CXCL16 is expressed on the surface of APCs including subsets of CD19(+) B cells and CD14(+) monocyte/macrophages, and functional CXCL16 is also shed from macrophages. CXCL16 is an alpha (CXC) chemokine but also has characteristics of CC chemokines and a structure similar to fractalkine (neurotactin) in having a transmembrane region and a chemokine domain suspended by a mucin-like stalk. CXCL16 may function in promoting interactions between DCs and CD8 T cells and in guiding T cell movements in the splenic red pulp. CXCL16 was also found in the thymic medulla and in some nonlymphoid tissues, indicating roles in thymocyte development and effector T cell trafficking.
參考文獻
Matloubian M, et al., 2000, Nat Immunol 1 (4): 298-304.
Wilbanks, A. et al., 2001, J Immunol 166 (8): 5145-54.
Abel, S. et al., 2004, J Immunol. 172 (10): 6362-72.

包裝：20ug

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查詢關鍵詞：重組小鼠 CXCL16 / SRPSOX 蛋白，C-X-C motif chemokine 16 ( CXCL16 / SRPSOX ) Protein ，原料藥，大包裝定制，現貨促銷，醫藥中間體，科學儀器，實驗室耗材，生化試劑，創賽中國,細胞因子
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