重組狗 IL-8 / CXCL8 蛋白|Interleukin 8 Protein|生產廠家|現貨

IL-8 / CXCL8蛋白產品信息
產品名稱：重組狗 IL-8 / CXCL8 蛋白|Interleukin 8 Protein|生產廠家|現貨
別名: IL8, CXCL8
表達方式: A DNA sequence encoding the canine IL8 (P41324) (Ala23-Pro101) was expressed, with a N-terminal Met.
種屬: Canine
表達宿主: E.coli

IL-8 / CXCL8 Protein QC Testing
純度: >95% as determined by SDS-PAGE SDS-PAGE
內**: Please contact us for more information.
穩定性: Samples are stable for up to twelve months from date of receipt at -70℃
預測N端: Ala 23
分子量: The recombinant canine IL8 comprises 80 amino acids and has a predicted molecular mass of 9.2 kDa. The apparent molecular mass of the protein is approximately 9 kDa in SDS-PAGE under reducing conditions due to glycosylation.
緩沖液: Lyophilized from sterile PBS 0.5mMTCEP PH7.4.
Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Please contact us for any concerns or special requirements.

IL-8 / CXCL8 Protein Usage Guide

儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
IL-8 / CXCL8蛋白背景綜述
Interleukin-8 (IL8), also known as CXCL8, is a member of the CXC chemokine family of small (8–10 kDa) proteins, a subfamily of chemokines within the cytokine superfamily. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli (IL-1, TNF, LPS, etc). IL8 has the N-terminal tripeptide Glu-Leu-Arg (ELR) motif, which is known to mediate IL8 receptor binding and subsequent signal transduction, such as the TRAF6- NF-κB pathway, and involved in inflammatory and allergic responses. Furthermore, it has been shown that IL8 also plays a vital role in angiogenesis which is important for tumorigenesis, progression and metastasis, and accordingly the expression levels of IL8 correlate with disease progression in several human carcinomas. Multiple N-terminal processed forms for this protein are available, and this purified IL8 (6-77 amino acids) is the most prominent one.
參考文獻
Baqqiolini M. et al., 1992, FEBS Lett. 307: 97-101.
Koch A.E. et al., 1992, Science. 258: 1798-1801.
Bar-Eli M. et al., 1999, Pathobiology. 67: 12-8.
Charalambous C. et al., 2005, Cancer. Res. 65: 10347-54.
Manna SK. et al., 2005, J Biol Chem. 280: 7010-21.

包裝：20ug

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查詢關鍵詞：重組狗 IL-8 / CXCL8 蛋白，Interleukin 8 Protein，生產廠家，現貨，原料藥，大包裝定制，現貨促銷，醫藥中間體，科學儀器，實驗室耗材，生化試劑，創賽中國,細胞因子
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