I-TAC / CXCL11蛋白產品信息 產品名稱:重組人 I-TAC / CXCL11 蛋白|Chemokine (C-X-C motif) ligand 11 Protein|廠家價格|參數 別名: CXCL11, ITAC, SCYB11, SCYB9B 表達方式: A DNA sequence encoding the mature form of human CXCL11(O14625) (Phe22-Phe94) was expressed with an initial Met. 種屬: Human 表達宿主: E.coli I-TAC / CXCL11 Protein QC Testing 純度: > 95 % as determined by SDS-PAGE SDS-PAGE 內**: Please contact us for more information. 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Met 分子量: The recombinant human CXCL11 consists of 73 amino acids and predicts a molecular mass of 8.3 KDa. It migrates as an approximately 9 KDa band in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile 40% acetonitrile, 1% TFA. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. I-TAC / CXCL11 Protein Usage Guide
儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. I-TAC / CXCL11蛋白背景綜述 I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. I-TAC is chemotactic for activated T cells. The CXCL11 gene is located on human chromosome 4 along with many other members of the CXC chemokine family. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. 參考文獻 Strausberg RL. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903. Rani MR. et al., 2002, J Biol Chem. 277 (41): 38456-61. Salmaggi A. et al., 2003, J Interferon Cytokine Res. 22 (6): 631-40. 包裝:20ug
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