CXCL14 / BRAK蛋白產品信息 產品名稱:重組人 CXCL14 / BRAK 蛋白|Chemokine (C-X-C motif) ligand 14 Protein|生產廠家|價格 別名: CXCL14, MIP2G, NJAC, SCYB14 表達方式: A DNA sequence encoding human CXCL14 (O95715) (Ser35-Glu111) was expressed with a N-terminal Met. 種屬: Human 表達宿主: E.coli CXCL14 / BRAK Protein QC Testing 純度: > 90 % as determined by SDS-PAGE SDS-PAGE 內**: Please contact us for more information. 穩定性: Samples are stable for up to twelve months from date of receipt at -70℃ 預測N端: Met 分子量: The recombinant human CXCL14 consists of 77 amino acids and predicts a molecular mass of 9.4 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions. 緩沖液: Lyophilized from sterile 100mM NaH2PO4, 1M NaCl, pH 6.5. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. Please contact us for any concerns or special requirements. CXCL14 / BRAK Protein Usage Guide 儲存方法: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. CXCL14 / BRAK蛋白背景綜述 CXCL14, also known as BRAK, is a small cytokine belonging to the CXC chemokine family. Members of this family are secreted proteins involved in immunoregulatory and inflammatory processes. CXCL14 is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. It is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. CXCL14 functions as a potent chemoattractant for neutrophils. It also has weaker attraction for dendritic cells. However, CXCL14 is not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. CXCL14 does not inhibit proliferation of myeloid progenitors in colony formation assays. 參考文獻 Tarnes T. et al., 2006, Exp Hematol. 34 (8): 1101-5. Shurin G V. et al., 2005, J Immun. 174: 5490-8. Kurth I. et al., 2001, J Exp Med. 194: 855-61. Frederick M J. et al., 2000, Am J Path. 156: 1937-50. 包裝:20ug
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